The phrase *in regards to (with a plural -s) seems to appear frequently (for the use of the asterisk read the comment at the end of this text). Even if it is common in texts by both native and non-native English writers, it is not correct.

When you want to refer to something, you can write in regard to or with regard to. Both phrases mean concerning. However, you have other alternatives:

regarding
in this regard
as regards
in respect of
with respect to
with reference to
relating to
on the subject of
in connection with
concerning
about
as for
re

Read about with respect to and in respect of here.

The verb regard can also mean look at, have or show respect for, think of with a particular feeling. The corresponding noun is used in phrases like the following:

I have great regard for his work.
Give my regards to your family.
Best regards.